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SpikedCola 1 hours ago [-]
Hamilton's Pharmacopia covers this topic, including an interview with the supposed author, then later corrected, then the true author revealed. Definitely worth checking out.
martinky24 2 hours ago [-]
Every time I find one of these in my backyard with my dog, I have to spray my dog’s mouth out with the hose for 5 minutes. Psychedelic, but also very toxic.
nxpnsv 1 hours ago [-]
Just my local regular non hallucinogenic toads makes dogs drewl like crazy if they try to catch on (or more commonly find a toad chip road kill on the gravel roads)
dreamcompiler 40 minutes ago [-]
Reminds me of the datura all over my yard. I keep chopping them down (while wearing gloves) but they keep coming back.
They're pretty but definitely a "look, don't eat" plant.
mettamage 3 hours ago [-]
Have any studies been done on this particular psychedelic? I'm curious.
pantalaimon 28 minutes ago [-]
It's 5-MeO-DMT, better to synthesize it than to exploit the toads for it though.
In the DMT world, carts are being sold known as Toad with the 5-MeO-DMT. Lots of very unhappy customers when they are not expecting it.
Aurornis 2 hours ago [-]
A couple groups are trying to commercialize it. There have been some trials, but they're all relatively limited by depression trial standards. Double-blind is impossible because the participants know 100% if they've received it or not. Someone volunteering to sign up for a depression study to receive psychedelic drugs is probably a believer that they work, so the placebo groups end up disappointed and the active groups are happy they got assigned the psychedelic they signed up.
They followed participants for 8 days, which is pretty disappointing. They really need to follow people for several months to see if anything holds or if it's a short-term placebo effect that wears off.
john_strinlai 2 hours ago [-]
plenty of scientific and not-really-scientific links available at erowid for 5-meo-dmt
This is an endangered species getting massively abused by the wellness "shaman" industry. It fucking sucks. Just use synthetic 5me0-dmt if you really must do a goofy vision quest larp.
martinky24 2 hours ago [-]
Hmm. I am all for leaving animals alone, but their Wikipedia page says their status is “secure” and of “least concern”.
So yeah, let the frogs be, but I don’t think we should invent (hallucinate, in this case, perhaps?) reasons why…
40 minutes ago [-]
RajT88 2 hours ago [-]
Find your soulmate, Homer!
juleiie 2 hours ago [-]
People really overthink drugs.
You don't need anything more than psilocybin and some weed from time to time.
Anything else is just unnecessary noise and introduces vulnerabilities to your Fortress of Mind.
Backdoor here, trapdoor here, tunnel there. Before you know it, your psyche collapses under all the brain neuroplasticity. Mind cannot form any shape at all.
Truly terrible thought so be careful my people. Don't malleableize yourself into a goo.
talon8635 1 hours ago [-]
I’ve used both a lot.
It’s inaccurate to frame weed and psilo as “necessary”.
natpalmer1776 2 hours ago [-]
YMMV by person, their neurochemistry, and their living environment. I need a stimulant for my specific biology to adapt to modern expectations.
juleiie 2 hours ago [-]
You don't need anything.
It is the bilion dollar industrial complex that sold you solution to the problem created by the very same system. Just take a pill.
It's ingenious really.
Create the problem, sell the solution.
I am rich generally speaking and I have privilege to see everything from my high vantage point.
From here I can easily see how life looks if you can afford to say: No thank you.
I don't even understand the very concept of suicide or depression. It seems fantastical. Because, I am outside the cruel system or rather I am at the steer in some capacity.
kcoul 1 hours ago [-]
this post just demonstrates the lack of sympathy/empathy so many rich people seem to have for others. There is a huge difference between taking pills designed to eternally treat symptoms and never the root cause, vs a plant medicine that might actually address the root cause of a problem. Bufo unfortunately has the added problem of coming from an animal rather than a plant, I agree with another post that suggests using synthetic where possible, but one should also not give up the opportunity to do life-changing personal development...
alecbz 32 minutes ago [-]
> understands people and knows what people need
> does not understand the concept of [incredibly common psychological problem]
denkmoon 47 minutes ago [-]
The type of mind that could genuinely benefit from a psychedelic…
jdanford 1 hours ago [-]
Your comment isn’t useful to anyone but you
thin_carapace 39 minutes ago [-]
I also think that the system is cruel to convince its cogs that it is acceptable to experience stress to the point of requiring hard drugs, and I think the person you're responding to has provided a valid counter example of what life can be like without such stress.
natpalmer1776 18 minutes ago [-]
Except I don’t use “hard drugs” I use a dose of Adderall prescribed to children to correct a specific chemical imbalance that is exceptionally well documented. I could, and did for a while, live without such medication and my basic quality of life was significantly worse. Not because of society, but because of my brain.
I am the person being told that I don’t need a stimulant by the condescending rich person, and I have to say that mental health is far too nuanced for casual armchair debate about how society is forcing people to need this drug or that drug.
The point I wanted to convey is that this topic is incredibly specific to the individual, and “generalizations” MUST use extensive qualifiers to even come close to being accurate.
john_strinlai 1 hours ago [-]
you have no idea who the person you are responding to is or what their circumstances are
nxpnsv 1 hours ago [-]
hmmm; I really don’t feel like I need weed or shrooms from time to time. I’m ok the way I am.
They're pretty but definitely a "look, don't eat" plant.
https://youtu.be/qipKKBmY_LQ
One of the latest studies: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/...
They followed participants for 8 days, which is pretty disappointing. They really need to follow people for several months to see if anything holds or if it's a short-term placebo effect that wears off.
https://www.erowid.org/chemicals/5meo_dmt/5meo_dmt.shtml
scientific references specifically at https://www.erowid.org/references/refs.php?S=5meo_dmt
Mebufotenin is 5-MeO-DMT
https://www.wsj.com/video/the-race-to-commercialize-the-worl...
https://www.newyorker.com/magazine/2022/03/28/the-pied-piper...
This is an endangered species getting massively abused by the wellness "shaman" industry. It fucking sucks. Just use synthetic 5me0-dmt if you really must do a goofy vision quest larp.
So yeah, let the frogs be, but I don’t think we should invent (hallucinate, in this case, perhaps?) reasons why…
You don't need anything more than psilocybin and some weed from time to time.
Anything else is just unnecessary noise and introduces vulnerabilities to your Fortress of Mind.
Backdoor here, trapdoor here, tunnel there. Before you know it, your psyche collapses under all the brain neuroplasticity. Mind cannot form any shape at all.
Truly terrible thought so be careful my people. Don't malleableize yourself into a goo.
It’s inaccurate to frame weed and psilo as “necessary”.
It is the bilion dollar industrial complex that sold you solution to the problem created by the very same system. Just take a pill.
It's ingenious really.
Create the problem, sell the solution.
I am rich generally speaking and I have privilege to see everything from my high vantage point. From here I can easily see how life looks if you can afford to say: No thank you.
I don't even understand the very concept of suicide or depression. It seems fantastical. Because, I am outside the cruel system or rather I am at the steer in some capacity.
> does not understand the concept of [incredibly common psychological problem]
I am the person being told that I don’t need a stimulant by the condescending rich person, and I have to say that mental health is far too nuanced for casual armchair debate about how society is forcing people to need this drug or that drug.
The point I wanted to convey is that this topic is incredibly specific to the individual, and “generalizations” MUST use extensive qualifiers to even come close to being accurate.
Anyone watch Hamiltons pharmacopeia